Shown to be effective for passive immunity against K99+ E. coli, bovine Coronavirus and bovine Rotavirus when administered within 12 hours of birth. Aids in the reduction of mortality and morbidity from scours caused by K99+ E. coli and Coronavirus while also reducing the severity and duration of scours caused by Rotavirus. USDA-approved veterinary biologic. Gel tube eliminates the need for dam and calf-level scours vaccinations. One dose provides immediate immunity - no need to stimulate immune response or follow-up with annual boosters. Guaranteed antibody levels in every dose - all calves are equally protected. Can be administered with colostrum, without the delay some calf-level vaccines require. Delivery is targeted to liveborn and valued calves, maximizing return on investment. No dam-level vaccine means less stress on the dam, increasing her response rate to critical vaccines, clearing room in her vaccination schedule.

Directions: Do not delay colostrum. For best results, gel should be administered to calves orally within 12 hours after birth. Place tube tip at back of throat; squeeze entire tube contents into calf's mouth, ensuring calf swallows all gel.

Disease Description:
The cause of neonatal calf diarrhea/scours is complex, but K99+ E. coli, coronavirus and rotavirus have been found to be 3 of its most common causative agents. Diarrhea/scours has been shown to make an animal more susceptible to secondary enteric and respiratory diseases.

Mode of Action:
Antibodies allow for passive immunity as they rapidly bind and neutralize targeted pathogens in the GI tract. When delivered prior to gut closure, antibodies are also absorbed into the bloodstream. Antibody products are compatible with colostrum, do not require vaccine induced system stress or lag time. The antibody levels for each of the active ingredients in First Defense Tri-Shield (E. coli, coronavirus and rotavirus) are measured and guaranteed to meet levels proven effective in controlled animal trials.

Safety and Efficacy:
In newborn/neonatal calves, First Defense Tri-Shield is a one-time preventative treatment against K99+ E. coli, coronavirus and rotavirus diarrhea/scours causing pathogens. No allergic or other adverse reactions were observed.

Vaccination has been the traditional way to protect calves from scours. But, First Defense Tri-Shield breaks tradition, providing a better way.

7 reasons to break from tradition:
3 vs. 2 Anti-Pathogens
Immediate vs. Delayed
Comfortable vs. Stressed Calves and Cows
Targeted vs. Wasted Investment
Easy vs. Complicated Delivery
Guaranteed vs. Variable
Progressive vs. Traditional

Anaphylactoid reactions may occur. Antidote : Epinephrine.

Learn More About Immucell First Defense Products