Used as an aid in the prevention of neonatal beef and dairy calf scours caused by K99+ E. coli and Coronavirus. Delivers specific antibodies to the gut for immediate protection against disease and provides additional immunoglobulins to be absorbed into the bloodstream for extended protection. Administer 1 bolus within the first 12 hours after birth. Do not vaccinate calves with oral Coronavirus or Rotavirus products within 5 days of administering First Defense. No slaughter withdrawal; approved for organic operations, check with with your certification agency. U.S. Lic. No. 327. For best administration results, use Medium Balling Gun (223-15, sold separately).